Litcius/Paper detail

Anticancer half-sandwich Ir(<scp>iii</scp>) complex and its interaction with various biomolecules and their mixtures – a case study with ascorbic acid

Lukáš Masaryk, Jakub Orvoš, Karolina Słoczyńska, Radovan Herchel, Ján Moncóľ, David Milde, Petr Halaš, Radka Křikavová, Paulina Koczurkiewicz, Elżbieta Pękala, Róbert Fischer, Ivan Šalitroš, Ivan Němec, Pavel Štarha

2022Inorganic Chemistry Frontiers21 citationsDOIOpen Access PDF

Abstract

An anticancer azo bond-containing half-sandwich Ir( iii ) complex oxidizes ascorbate to dehydroascorbate, and ascorbate recovers in the presence of reduced glutathione.

Topics & Concepts

Ascorbic acidChemistryGlutathioneBiomoleculeCombinatorial chemistryDehydroascorbic acidStereochemistryBiochemistryFood scienceEnzymeMetal complexes synthesis and propertiesLanthanide and Transition Metal ComplexesMetal-Organic Frameworks: Synthesis and Applications