Litcius/Paper detail

Anabolic androgenic steroid abuse in young males

Willem de Ronde, Diederik L. Smit

2020Endocrine Connections132 citationsDOIOpen Access PDF

Abstract

This review summarizes 10 years experience with male abusers of anabolic androgenic steroids (AAS). The typical user of AAS is male, aged between 20 and 40 and lifting weights. Illegal AAS are cheap and easily obtained via internet or local suppliers. AAS are mostly used in cycles with a duration between 6 and 18 weeks. Most AAS cycles contain multiple agents, used simultaneously in a dose vastly exceeding a substitution dose. A variety of other performance and image-enhancing drugs are commonly used, including human growth hormone, thyroid hormone, tamoxifen, clomiphene citrate and human chorionic gonadotrophin. Short-term clinical and biochemical side effects are well established. Long-term side effects are uncertain, but may include heart failure, mood-and anxiety disorders, hypogonadism and subfertility. We share our views on the management of common health problems associated with AAS abuse.

Topics & Concepts

MedicineTestosterone (patch)AnxietyHormoneMoodSubstance abuseMood disordersEndocrinologyInternal medicinePhysiologyPsychiatryHormonal and reproductive studiesSexual Differentiation and DisordersMuscle metabolism and nutrition