Exosomal STIMATE derived from type II alveolar epithelial cells controls metabolic reprogramming of tissue-resident alveolar macrophages
Zunyong Feng, Jing Zhou, Qiang Li, Liuxi Chu, Yuxin Jiang, Xuanbo Zhang, Liang Yan, Yinhua Liu, Jing Jiang, Ping Xu, Qun Chen, Ming Wang, Hui Yang, Guoren Zhou, Xiaochun Jiang, Xiaoyuan Chen, Hongping Xia
Abstract
ADEs lessened early acute injury, prevented advanced fibrosis, alleviated ventilatory impairment and reduced mortality.
Topics & Concepts
FibrosisBronchoalveolar lavagePulmonary fibrosisLung transplantationImmunologyLungIdiopathic pulmonary fibrosisImmune systemMedicineCancer researchBiologyPathologyInternal medicineExtracellular vesicles in diseaseInflammasome and immune disordersPhagocytosis and Immune Regulation