Synthesis and properties of 1-(3-fluoroadamantan-1-yl)-3-R-ureas and 1,1′-(alkan-1,n-diyl)bis[3-(3-fluoroadamantan-1-yl)ureas], promising inhibitors of epoxide hydrolase sEH
B. P. Gladkikh, Д. В. Данилов, V. S. D’yachenko, В. В. Бурмистров, Г. М. Бутов, И. А. Новаков
Topics & Concepts
ChemistryEpoxide hydrolase 2MethyleneYield (engineering)ReagentAdamantaneFluorineEpoxideUreaBenzoic acidAzideOrganic chemistryMelting pointMedicinal chemistryStereochemistryEnzymeMaterials scienceMetallurgyCatalysisEicosanoids and Hypertension PharmacologyNitric Oxide and Endothelin EffectsHormonal Regulation and Hypertension