Perioperative neurocognitive disorders: Advances in molecular mechanisms and bioactive molecules
Liwei Mao, L. M. Wang, Zhihai Huang, Jeffrey A. Switzer, David Hess, Quanguang Zhang
Abstract
and NMDA receptors. Additionally, we highlight the roles of epigenetic regulation and gut microbiota dysbiosis in sustaining neuroinflammation and cognitive deficits. Finally, we explore potential therapeutic strategies, including bioactive compounds and neuroprotective agents, offering new directions for the prevention and treatment of PNDs.
Topics & Concepts
NeurocognitivePerioperativeNeuroscienceMedicineComputational biologyPharmacologyBioinformaticsPsychologyBiologyCognitionAnesthesiaIntensive Care Unit Cognitive DisordersAnesthesia and Neurotoxicity ResearchCardiac, Anesthesia and Surgical Outcomes