Structure determination, correction, and disproof of marine macrolide natural products by chemical synthesis
Haruhiko Fuwa
Abstract
Integration of chemical synthesis, NMR spectroscopy, and various analytical means is key to success in the structure elucidation of stereochemically complex marine macrolide natural products.
Topics & Concepts
ChemistryKey (lock)Natural (archaeology)Nuclear magnetic resonance spectroscopyChemical structureStereochemistryCombinatorial chemistryOrganic chemistryEcologyHistoryBiologyArchaeologySynthetic Organic Chemistry MethodsMarine Sponges and Natural ProductsAsymmetric Synthesis and Catalysis