CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism
Hyelim Cho, Qiong Shen, Lydia H. Zhang, Mikiko Okumura, Akinori Kawakami, Jessi Ambrose, Frederic Sigoillot, Howard Miller, Scott Gleim, Amanda Cobos‐Correa, Ying Wang, Philippe Piéchon, Guglielmo Roma, Fabian Eggimann, Charles M. Moore, Peter Aspesi, Felipa Mapa, Heather Burks, Nathan T. Ross, Philipp Krastel, Marc Hild, Thomas J. Maimone, David E. Fisher, Daniel K. Nomura, John A. Tallarico, Stephen M. Canham, Jeremy L. Jenkins, William C. Forrester
Topics & Concepts
Microphthalmia-associated transcription factorBiologyMitochondrionMitochondrial biogenesisNeuroblastoma RAS viral oncogene homologCell biologyTranscription factorBiochemistryCancer researchGeneMutationKRASPhytochemical compounds biological activitiesMicrobial Natural Products and BiosynthesisMelanoma and MAPK Pathways