TJ-M2010-5, a novel MyD88 inhibitor, corrects R848-induced lupus-like immune disorders of B cells in vitro
Zhimiao Zou, Dunfeng Du, Miao Yan, Yang Yang, Yalong Xie, Zeyang Li, Liang Zhou, Limin Zhang, Ping Zhou, Fengchao Jiang
Topics & Concepts
TLR7Systemic lupus erythematosusAutoantibodyImmune systemBiologyImmunologyInflammationIn vitroB cellToll-like receptorApoptosisMAPK/ERK pathwayCell biologySignal transductionInnate immune systemMedicineAntibodyInternal medicineDiseaseBiochemistryT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmune Response and Inflammation