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Annulated pyrazole derivatives as a novel class of urokinase (uPA) inhibitors: Green synthesis, anticancer activity, DNA-damage evaluation, and molecular modelling study

Paula S. Farag, Asmaa M. AboulMagd, Magdy M. Hemdan, Aya I. Hassaballah

2022Bioorganic Chemistry31 citationsDOI

Topics & Concepts

ChemistryIC50Cell cultureDoxorubicinCytotoxicityPyrazoleStereochemistryCytotoxic T cellIn vitroPharmacologyBiochemistryChemotherapyBiologyGeneticsSynthesis and biological activityPhytochemical compounds biological activitiesClick Chemistry and Applications
Annulated pyrazole derivatives as a novel class of urokinase (uPA) inhibitors: Green synthesis, anticancer activity, DNA-damage evaluation, and molecular modelling study | Litcius