Orientin alleviates ox-LDL-induced oxidative stress, inflammation and apoptosis in human vascular endothelial cells by regulating Sestrin 1 (SESN1)-mediated autophagy
Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou
Topics & Concepts
AutophagyOrientinOxidative stressApoptosisPI3K/AKT/mTOR pathwayAMPKChemistryViability assayCell biologyWestern blotInflammationPharmacologyBiologyVitexinImmunologyBiochemistryPhosphorylationGeneFlavonoidProtein kinase AAntioxidantAutophagy in Disease and TherapyCalpain Protease Function and RegulationSirtuins and Resveratrol in Medicine