Hybrid micelles enhance tumour therapy by remodelling biodistribution and improving intracellular drug release
Xuhan Liu, Wei Liu, Jiafa Lu, Qin Li, Wei Han
Abstract
44.5%). Furthermore, the hybrid micelles exhibited low hemolysis and reduced deposition in normal organs, which revealed their excellent bio-safety. Therefore, we established a promising hybrid micelle system for efficient anti-tumour therapy.
Topics & Concepts
MicelleEthylene glycolBiodistributionChemistryPEG ratioIntracellularDrugBiophysicsDrug carrierPEGylationDrug deliveryPharmacologyBiochemistryPolyethylene glycolOrganic chemistryMedicineBiologyIn vitroAqueous solutionFinanceEconomicsNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsCancer Research and Treatments