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Orlistat delays hepatocarcinogenesis in mice with hepatic co-activation of AKT and c-Met

Cong Zhang, Lei Sheng, Ming Yuan, Junjie Hu, Yan Meng, Yong Wu, Liang Chen, Huifan Yu, Shan Li, Guohua Zheng, Zhenpeng Qiu

2020Toxicology and Applied Pharmacology23 citationsDOI

Topics & Concepts

OrlistatProtein kinase BCancer researchPI3K/AKT/mTOR pathwayLipogenesisIn vivoPTENHepatocellular carcinomaSteatosisHCCSPharmacologyMedicineInternal medicineChemistrySignal transductionBiologyBiochemistryLipid metabolismObesityWeight lossBiotechnologyCancer, Lipids, and MetabolismPeroxisome Proliferator-Activated ReceptorsCancer, Hypoxia, and Metabolism
Orlistat delays hepatocarcinogenesis in mice with hepatic co-activation of AKT and c-Met | Litcius