Molecular hydrogen enhances osteogenesis in <i>Danio rerio</i> embryos
Marta Carnovali, Massimo Mariotti, Giuseppe Banfi
Abstract
) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because of its transparency, size and rapid development. In zebrafish embryo, hydrogen-rich water (HRW) does not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances zebrafish embryo osteogenesis, increasing the vertebral mineralization rate. In conclusion, we demonstrated the beneficial effects of hydrogen on anabolic bone functions in vivo.
Topics & Concepts
DanioZebrafishEmbryoBiologyIn vivoAnabolismCell biologyAnatomyGeneticsEndocrinologyGeneHydrogen's biological and therapeutic effectsAnesthesia and Neurotoxicity ResearchBiochemical effects in animals