Litcius/Paper detail

Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease

Matthew Bratkowski, Thomas C. Burdett, Jean Danao, Xidao Wang, Prakhyat Mathur, Weijing Gu, Jennifer A. Beckstead, Santosh Talreja, Yu-San Yang, Gregory Danko, Jae Hong Park, Mary Walton, Sean P. Brown, Christopher M. Tegley, Prem Raj B. Joseph, Charles H. Reynolds, Shilpa Sambashivan

2022Neuron65 citationsDOIOpen Access PDF

Topics & Concepts

NeuroprotectionNAD+ kinaseNicotinamide adenine dinucleotideCD38PharmacologyNeuroscienceBiochemistrySmall moleculeBiologyChemistryEnzymeCell biologyCD34Stem cellCalcium signaling and nucleotide metabolismSignaling Pathways in DiseaseCellular transport and secretion