Redox sensitive nano-capsules self-assembled from hyaluronic acid-hydroxychloroquine conjugates for CD44-targeted delivery of hydroxychloroquine to combat breast cancer metastasis in vitro and in vivo
Yang He, Yanyun Xu, Yushu Huang, Hao Quang, Xiaoyan Xia, Hongbo Zhao, Yi Xiao, Wei Lü, Jiahui Yu
Topics & Concepts
NanocapsulesChemistryIn vivoHyaluronic acidHydroxychloroquineBiophysicsIn vitroCancer cellPharmacologyCancer researchBiochemistryMaterials scienceNanotechnologyCancerMedicineBiologyPathologyNanoparticleInternal medicineAnatomyInfectious disease (medical specialty)BiotechnologyDiseaseCoronavirus disease 2019 (COVID-19)Nanoplatforms for cancer theranosticsDendrimers and Hyperbranched PolymersChemokine receptors and signaling