Litcius/Paper detail

Design and synthesis of new series of chiral pyrimidine and purine analogs as COX-2 inhibitors: Anticancer screening, molecular modeling, and in silico studies

Aisha Y. Hassan, Eman S. Abou‐Amra, Samiha A. El‐Sebaey

2023Journal of Molecular Structure16 citationsDOI

Topics & Concepts

ChemistryPyrimidinePurineStereochemistryPurine analogueDoxorubicinIC50Cell cultureIn silicoIn vitroBiochemistryEnzymeChemotherapyInternal medicineBiologyGeneGeneticsMedicineSynthesis and biological activitySynthesis and Biological EvaluationInflammatory mediators and NSAID effects