Puerarin induces Nrf2 as a cytoprotective mechanism to prevent cadmium-induced autophagy inhibition and NLRP3 inflammasome activation in AML12 hepatic cells
Zhao-Ming Yu, Xuemei Wan, Min Xiao, Chuan Zheng, Xue-Lei Zhou
Topics & Concepts
AutophagyChemistryInflammasomeCell biologyKEAP1CytoprotectionGene silencingGene knockdownHepatocyteOxidative stressATG5ApoptosisBiochemistryBiologyTranscription factorReceptorGeneIn vitroHeavy Metal Exposure and ToxicityCurcumin's Biomedical ApplicationsAutophagy in Disease and Therapy