Smartphone surface plasmon resonance imaging for the simultaneous and sensitive detection of acute kidney injury biomarkers with noninvasive urinalysis
Qingwen Zhang, Yang Li, Qianqian Hu, Ruifeng Xie, Wenjing Zhou, Xiaohu Liu, Xiaohu Liu
Abstract
for the simultaneous detection of neutrophil gelatinase-associated lipocalin (NGAL), interleukin-18 (IL-18) and retinol-binding protein (RBP) in urine, respectively. The biosensors demonstrated high specificity and sensitivity for the simultaneous detection of multiple AKI biomarkers in PBST and urine. The smartphone SPRi system provided a portable and cost-effective platform for point-of-care diagnosis, in-field healthcare and environmental monitoring.
Topics & Concepts
Surface plasmon resonanceDetection limitUrinalysisMagnetic resonance imagingBiomedical engineeringMaterials scienceUrineChemistryNanotechnologyMedicineNanoparticleChromatographyInternal medicineRadiologyBiosensors and Analytical DetectionRetinal and Optic ConditionsNanoplatforms for cancer theranostics