Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis
Yining Liu, Wenyan Chen, Yanli Cen, Xiaodeng Zhao, Zaiping Chen, Yuedong Liang, Zhongfeng Huang, He Xiu, Guanghong Yang
Topics & Concepts
HepatocyteIn vivoLipid peroxidationLiver injuryGPX4PharmacologyDrugProgrammed cell deathGene knockdownIn vitroCancer researchChemistryMedicineBiologyAntioxidantBiochemistryApoptosisBiotechnologyCatalaseGlutathione peroxidaseFerroptosis and cancer prognosisDrug Transport and Resistance MechanismsCancer, Lipids, and Metabolism