The hypoxic ECM and neutrophils in MIBC immunotherapy resistance
Fraser Child, Sapna Lunj, Julie E. Gough, Martin J. Humphries, Luisa Vanesa Biolatti, Peter Hoskin, Ananya Choudhury, Conrado Guerrero Quiles
Topics & Concepts
MedicineImmunotherapyExtracellular matrixNeutrophil extracellular trapsHypoxia (environmental)Cancer researchBladder cancerInfiltration (HVAC)ImmunologyProgrammed cell deathCancer immunotherapyCellImmune systemGranulocyteTumor microenvironmentPD-L1ReceptorSignal transductionCancerCombination therapyImmune cells in cancerBladder and Urothelial Cancer TreatmentsNanoplatforms for cancer theranostics