Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis
N. Yan, Gareth J. Morgan, H. Michael Petrassi, Ian A. Wilson, Jeffery W. Kelly
Topics & Concepts
Immunoglobulin light chainChemistryAntibodyBiophysicsSmall moleculeAmyloidosisBiochemistryBiologyMedicineImmunologyInternal medicineAmyloidosis: Diagnosis, Treatment, OutcomesProtein Kinase Regulation and GTPase SignalingCaveolin-1 and cellular processes