Design, synthesis and mechanistic studies of benzophenones hydrazone derivatives as cathepsin inhibitors
Israa A. Abdel-Azziz, Noha H. Amin, Mohammed T. El‐Saadi, Hamdy M. Abdel‐Rahman
Topics & Concepts
ChemistryBenzophenoneHydrazoneADMEStereochemistryCathepsin BCell cultureApoptosisHT1080Cathepsin LCathepsinEnzymeIn vitroBiochemistryOrganic chemistryBiologyGeneticsBone Metabolism and DiseasesProtease and Inhibitor MechanismsNatural product bioactivities and synthesis