Supramolecular Hydrogel Based on an Osteogenic Growth Peptide Promotes Bone Defect Repair
Yanhong Zhao, Yi Xing, Min Wang, Ying Huang, Xu H, Yuran Su, Yanmei Zhao, Yuna Shang
Abstract
was evaluated. The results showed that the hydrogels promoted bone formation in the early stage of bone defect healing. Taken together, this study was the first to develop and evaluate the properties of OGP-based self-assembling supramolecular hydrogels. Our study will provide inspiration for the development of delivering OGP for bone regeneration.
Topics & Concepts
Self-healing hydrogelsRUNX2Bone morphogenetic protein 2Bone healingIn vivoCell biologyRegeneration (biology)ChemistryBiocompatibilityPeptideBiomedical engineeringMaterials scienceOsteoblastBiophysicsIn vitroBiochemistryAnatomyBiologyMedicineBiotechnologyOrganic chemistrySupramolecular Self-Assembly in MaterialsBone and Dental Protein StudiesPeptidase Inhibition and Analysis