Comprehensive phenotyping of endothelial cells using flow cytometry 2: Human
Dillon Grant, Nicholas Wanner, Matthew Frimel, Serpil C. Erzurum, Kewal Asosingh
Abstract
Abstract In vascular research, clinical samples and samples from animal models are often used together to foster translation of preclinical findings to humans. General concepts of endothelia and murine‐specific endothelial phenotypes were discussed in part 1 of this two part series. Here, in part 2, we present a comprehensive overview of human‐specific endothelial phenotypes. Pan‐endothelial cell markers, organ specific endothelial antigens, and flow cytometric immunophenotyping of blood‐borne endothelial cells are reviewed.
Topics & Concepts
Flow cytometryCytometryComputational biologyCell biologyBiologyChemistryMolecular biologyAngiogenesis and VEGF in CancerLymphatic System and DiseasesZebrafish Biomedical Research Applications