Stereoselective Three-Component Carbocyclization of 1,7-Enynes with Sulfoxonium Ylides and Water under Photoredox Catalysis
Ning Xian, Jiang Yin, Xiaochen Ji, Guo‐Jun Deng, Huawen Huang
Abstract
A visible-light-induced photoredox three-component carbocyclization reaction of 1,7-enynes with sulfoxonium ylides and water is reported. The protocol provides a facile entry to structurally valuable highly functionalized cyclopenta[ c ]quinoline scaffolds in a highly chemoselective and stereoselective manner. Salient features of this method include facile redox-neutral conditions, no requirement of base or other additive, and good functional-group tolerance.
Topics & Concepts
ChemistryStereoselectivityQuinolineCatalysisCombinatorial chemistryComponent (thermodynamics)Functional groupBase (topology)Organic chemistryPolymerMathematical analysisMathematicsThermodynamicsPhysicsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesRadical Photochemical Reactions