Co-surfactant effect of polyethylene glycol 400 on microemulsion using BCS class II model drug
Salam Shanta Taher, Khalid Kadhem Al-Kinani, Zahraa Mohsen Hammoudi, Mowafaq M. Ghareeb
Abstract
Microemulsions are an intriguing method for delivering poorly soluble drugs, protecting labile drugs, controlling drug release, and increasing drug bioavailability. They can be given topically, orally, or intravenously, and use polyethylene glycol (PEG-400) as a co-surfactant to improve the solubility and stability of biological classification system (BCS) class II drugs. The goal of this research is to develop and test an oil-in-water (O/W) microemulsion-based formulation to improve the solubil
Topics & Concepts
Pulmonary surfactantPolyethylene glycolMicroemulsionChemistryDrugChromatographyMaterials scienceChemical engineeringPharmacologyOrganic chemistryMedicineBiochemistryEngineeringAdvancements in Transdermal Drug DeliveryDrug Solubulity and Delivery SystemsSurfactants and Colloidal Systems