Acylation of Arenes with Aldehydes through Dual C–H Activations by Merging Photocatalysis and Palladium Catalysis
Haiyang Wang, Tao Li, Dongyan Hu, Xiaogang Tong, Liyan Zheng, Chengfeng Xia
Abstract
An acylation of arenes with aldehydes through dual C-H activations at room temperature is reported. The acylation was initiated by phenanthraquinone-catalyzed hydrogen atom transfer from aldehyde under visible light irradiation. The aldehyde-derived acyl radical merged with palladium-catalyzed activation of arenes to afford the cross coupling products.
Topics & Concepts
ChemistryAcylationAldehydeCatalysisPalladiumPhotocatalysisHydrogen atomPhotochemistryOrganic chemistryCombinatorial chemistryGroup (periodic table)Radical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques