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Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation

Erhao Zhang, Yichao Wang, Hongli Zhang, Xiaomin Li, Yijing Su, Jianan Cui, Rui‐Hua Xu, Xue Mao, Mengmeng Sang, Zenghua Lin, Xiaorong Zhou

2025Free Radical Biology and Medicine16 citationsDOI

Topics & Concepts

Triple-negative breast cancerGPX4Cancer researchChemistryCancer cellApoptosisProgrammed cell deathIn vivoResveratrolCell biologyLipid peroxidationGlutathioneBiologyCancerOxidative stressBiochemistryBreast cancerGlutathione peroxidaseGeneticsEnzymeBiotechnologyFerroptosis and cancer prognosisCancer, Lipids, and MetabolismRNA modifications and cancer
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation | Litcius