Development of Methods to the Synthesis of β‐Boryl Acyls, Imines and Nitriles
Kanak Kanti Das, Somenath Mahato, Subrata Hazra, Santanu Panda
Abstract
Organoboron compounds are highly important and versatile synthetic intermediates for the preparation of a wide range of organic molecules. Organoboron compounds have drawn significant attention among organic chemists due to their Lewis acidic property, non-toxicity, and commercial availability. Over the last several decades, there has been a substantial development of new organoboron compounds, useful in organic synthesis. Among all other organoboron compounds, β-boryl carbonyl compounds are the important ones. The β-boryl compounds have appeared as promising intermediates for various synthetic transformations. The 1,4-conjugate addition of diboron reagents to carbon-carbon double bond in the presence of different transition-metal catalysts has been extensively reported by various research groups across the globe. This mini-review outlines the numerous racemic as well as asymmetric β-borylation methods developed to date.