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Antifungal Polymer Containing Menthoxy Triazine

Xuefei Li, Zixu Xie, Guofeng Li, Lei Tao, Yen Wei, Xing Wang

2021ACS Applied Polymer Materials11 citationsDOI

Abstract

An antifungal polymer containing menthoxy triazine was synthesized by a polycondensation of 2,4-dichloro-6-menthoxy-1,3,5-triazine (DMT) with 4,4-oxidianiline (ODA) and named as P(MT-alt-ODA). To emphasize the antifungal performance of the menthoxy group, series of similar triazine polymers derived correspondingly with hydrogen, ethoxy, and decoxy groups were prepared and served as controls. The spores of Aspergillus niger were used for an antifungal evaluation. Only P(MT-alt-ODA) can effectively inhibit the growth and spread of spores. A further in-depth analysis combined with an inhibition zone and water contact angle illustrated that the surface menthoxy stereochemistry is crucial for the antifungal mechanism.

Topics & Concepts

AntifungalAspergillus nigerAlkoxy groupTriazinePolymerChemistrySporeStereochemistryNuclear chemistryOrganic chemistryMicrobiologyBiochemistryBiologyAlkylSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Biological EvaluationClick Chemistry and Applications
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