Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine)
Mitsuru Naito, Hiroyuki Chaya, Kazuko Toh, Beob Soo Kim, Kotaro Hayashi, Shigeto Fukushima, Tetsuya Nagata, Takanori Yokota, Kazunori Kataoka, Kanjiro Miyata
Topics & Concepts
Ethylene glycolOligonucleotideChemistryPEG ratioBlock (permutation group theory)Combinatorial chemistryLysineBiochemistryOrganic chemistryDNAAmino acidMathematicsGeometryEconomicsFinanceRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryDendrimers and Hyperbranched Polymers