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Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction

Fazhen Luo, Juanjuan Zhao, Shuo Liu, Yuanfei Xue, Dongyun Tang, Jun Yang, Mei Ye, Guowen Li, Yan Xie

2022Biochemical Pharmacology26 citationsDOI

Topics & Concepts

AMPKUrsolic acidCancer researchPI3K/AKT/mTOR pathwayDoxorubicinPharmacologyCell growthApoptosisChemistryViability assayProtein kinase BBiologyCell biologyMedicineInternal medicineBiochemistryKinaseProtein kinase AChemotherapyChromatographyNatural product bioactivities and synthesisRetinoids in leukemia and cellular processesATP Synthase and ATPases Research
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction | Litcius