Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain
Gabriel I. Small, Olga Fedorova, Paul Dominic B. Olinares, Joshua Chandanani, Anoosha Banerjee, Young Joo Choi, Henrik Molina, Brian T. Chait, Seth A. Darst, Elizabeth A. Campbell
Topics & Concepts
BiologyEnzymeGTP'RNABiophysicsComputational biologyAllosteric regulationNucleotideDivalentCell biologyBiochemistryChemistryGeneOrganic chemistryinterferon and immune responsesRNA and protein synthesis mechanismsViral gastroenteritis research and epidemiology