Glutamate delta 1 receptor regulates autophagy mechanisms and affects excitatory synapse maturation in the somatosensory cortex
Dinesh Y. Gawande, Kishore Kumar S. Narasimhan, Jay M. Bhatt, Ratnamala Pavuluri, Varun Kesherwani, Pratyush Suryavanshi, Gajanan P. Shelkar, Shashank M. Dravid
Topics & Concepts
NeuroscienceGlutamate receptorPI3K/AKT/mTOR pathwayHippocampusExcitatory postsynaptic potentialPrefrontal cortexAutophagyConditional gene knockoutPhenotypeBiologyDendritic spineAMPA receptorCell biologyChemistryReceptorSignal transductionInhibitory postsynaptic potentialGeneGeneticsCognitionHippocampal formationApoptosisNeuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental DisordersAutophagy in Disease and Therapy