Hypermethylation of Mitochondrial Cytochrome b and Cytochrome c Oxidase II Genes with Decreased Mitochondrial DNA Copy Numbers in the APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease
Yingying Xu, Ling Jie Cheng, Jing Sun, Fan Li, Xiangtian Liu, Yan Wei, Min Han, Zhengyu Zhu, Jianzhong Bi, Chao Lai, Yun Wang
Topics & Concepts
Mitochondrial DNABiologyCytochrome c oxidaseDNA methylationMolecular biologyMitochondrionMethylationCpG siteGeneticsHuman mitochondrial geneticsGeneGene expressionEpigenetics and DNA MethylationMitochondrial Function and PathologyAmino Acid Enzymes and Metabolism