MOF effectively deliver CRISPR and enhance gene-editing efficiency via MOF’s hydrolytic activity of phosphate ester bonds
Yang Wang, Zhibo Liu, Hongyan Zhang, Jia Liu, Hongmei Dai, Tiantian Ji, Feng Liu, Peng Cao, Jinhui Zou, Shuai Wang, Lin Wang, Zheng Wang
Topics & Concepts
CRISPRGenome editingGeneComputational biologyChemistryGene clusterPlasmidMutagenesisCombinatorial chemistryBiochemistryBiologyMutationAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringRNA Interference and Gene Delivery