Progress in exosomes and their potential use in ocular diseases
Sufang Li
Abstract
Exosomes contain a variety of biological active substances such as proteins, miRNAs, lncRNAs and lipids, and exosomes from different cells play different biological functions. Exosomes, as a carrier, are involved in many pathological processes such as nerve injury and repair, vascular regeneration, immune response, and fibrosis formation. It plays an important role in the treatment of eye diseases such as glaucoma, diabetic retinopathy, and keratitis. This paper reviews the research progress of exosomes in various diseases in vivo, which provides a new way for the treatment of eye diseases.
Topics & Concepts
MicrovesiclesMedicineRegeneration (biology)Diabetic retinopathyImmune systemmicroRNAGlaucomaFibrosisBioinformaticsNeuroscienceImmunologyCell biologyPathologyOphthalmologyBiologyDiabetes mellitusGeneBiochemistryEndocrinologyExtracellular vesicles in diseaseMicroRNA in disease regulationOcular Diseases and Behçet’s Syndrome