Adaptation induced by self-targeting in a type I-B CRISPR-Cas system
Aris-Edda Stachler, Julia Wörtz, Omer S. Alkhnbashi, Israela Turgeman-Grott, Rachel Smith, Thorsten Allers, Rolf Backofen, Uri Gophna, Anita Marchfelder
Abstract
that operates at low basal levels and is induced by DNA breaks.
Topics & Concepts
Haloferax volcaniiCRISPRBiologyGenome engineeringGenomeProkaryoteDNAGeneticsHomologous recombinationGeneGenome editingComputational biologyArchaeaCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniques