Induction of ferroptosis by HO-1 contributes to retinal degeneration in mice with defective clearance of all-trans-retinal
Chao Chen, Kunhuan Yang, Danxue He, Bo Yang, Lei Tao, Jingmeng Chen, Yalin Wu
Topics & Concepts
Cell biologyRetinal pigment epitheliumPhotoreceptor cellRetinal degenerationRetinalRetinal regenerationBiologyRetinaVisual phototransductionHeme oxygenaseProgrammed cell deathReactive oxygen speciesChemistryDrusenLipofuscinApoptosisHemeGeneticsBiochemistryRegeneration (biology)EnzymeNeuroscienceHeme Oxygenase-1 and Carbon MonoxideAir Quality and Health ImpactsRedox biology and oxidative stress