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Multicomponent reaction for the synthesis of new 1,3,4-thiadiazole-thiazolidine-4-one molecular hybrids as promising antidiabetic agents through α-glucosidase and α-amylase inhibition

Lalitha Gummidi, Nagaraju Kerru, Oluwakemi Ebenezer, Paul Awolade, Olakunle Sanni, Md. Shahidul Islam, Parvesh Singh

2021Bioorganic Chemistry69 citationsDOI

Topics & Concepts

ChemistryAcarboseThiazolidineIC50StereochemistryCombinatorial chemistryIn vitroAmylaseAntimicrobialEnzymeBiochemistryOrganic chemistrySynthesis and biological activityMulticomponent Synthesis of HeterocyclesClick Chemistry and Applications
Multicomponent reaction for the synthesis of new 1,3,4-thiadiazole-thiazolidine-4-one molecular hybrids as promising antidiabetic agents through α-glucosidase and α-amylase inhibition | Litcius