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Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Tahereh Seifi, Ali Reza Kamali

2021Medicine in Drug Discovery85 citationsDOIOpen Access PDF

Abstract

Coronavirus disease-2019 has been one of the most challenging global epidemics of modern times with a large number of casualties combined with economic hardships across the world. Considering that there is still no definitive cure for the recent viral crisis, this article provides a review of nanomaterials with antiviral activity, with an emphasis on graphene and its derivatives, including graphene oxide, reduced graphene oxide and graphene quantum dots. The possible interactions between surfaces of such nanostructured materials with coronaviruses are discussed. The antiviral mechanisms of graphene materials can be related to events such as the inactivation of virus and/or the host cell receptor, electrostatic trapping and physico-chemical destruction of viral species. These effects can be enhanced by functionalization and/or decoration of carbons with species that enhances graphene-virus interactions. The low-cost and large-scale preparation of graphene materials with enhanced antiviral performances is an interesting research direction to be explored.

Topics & Concepts

GrapheneNanotechnologyCoronavirus disease 2019 (COVID-19)OxideNanomaterialsSurface modificationMaterials scienceSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ChemistryDiseaseMedicineInfectious disease (medical specialty)MetallurgyPathologyPhysical chemistryGraphene and Nanomaterials ApplicationsCarbon and Quantum Dots ApplicationsSARS-CoV-2 detection and testing
Antiviral performance of graphene-based materials with emphasis on COVID-19: A review | Litcius