Allometric Scaling in Pharmacokinetic Studies in Anesthesiology
Douglas J. Eleveld, Jeroen V. Koomen, Anthony R. Absalom, Hong Su, Laura N. Hannivoort, Michel M. R. F. Struys
Abstract
In Brief A clinical review is presented of basic allometric scaling theory and its application to pharmacokinetic models in anesthesia and other fields in the biologic sciences.
Topics & Concepts
MedicineAllometryPharmacokineticsAnesthesiologyScalingAnesthesiaIntensive care medicineMEDLINEMetabolic clearance rateStatisticsPharmacologyScaling lawQuantileComputational Drug Discovery MethodsPharmacogenetics and Drug MetabolismAdvanced Physical and Chemical Molecular Interactions