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Specific Interaction of Novel<i>Friunavirus</i>Phages Encoding Tailspike Depolymerases with Corresponding Acinetobacter baumannii Capsular Types

Anastasiya V. Popova, Mikhail M. Shneider, N. P. Arbatsky, Anastasiya A. Kasimova, Sof’ya N. Senchenkova, Alexander S. Shashkov, Andrey S. Dmitrenok, Alexander O. Chizhov, Yulia V. Mikhailova, Dmitry A. Shagin, Olga S. Sokolova, Olga Y. Timoshina, Roman S. Kozlov, Konstantin A. Miroshnikov, Yuriy A. Knirel

2020Journal of Virology63 citationsDOIOpen Access PDF

Abstract

Acinetobacter baumannii , a nonfermentative, Gram-negative, aerobic bacterium, is one of the most significant nosocomial pathogens. The pathogenicity of A. baumannii is based on the cooperative action of many factors, one of them being the production of capsular polysaccharides (CPSs) that surround bacterial cells with a thick protective layer.

Topics & Concepts

Acinetobacter baumanniiBiologyMicrobiologyGenomeBacteriophageRecombinant DNAEscherichia coliGeneBacteriaGeneticsPseudomonas aeruginosaBacteriophages and microbial interactionsMicrobial infections and disease researchBacterial Genetics and Biotechnology