Shape Memory Polymer Foams with Tunable Degradation Profiles
Anand Utpal Vakil, Natalie Marie Petryk, Ellen Shepherd, Henry T. Beaman, Priya S. Ganesh, Katheryn Shi Dong, Mary Beth Browning Monroe
Abstract
(oxidation) and 0.1 M NaOH (hydrolysis) at 37 °C). The resulting foams had tunable, clinically relevant degradation rates, with complete mass loss within 30-60 days. These SMP foams have potential to provide an easy-to-use, shape-filling hemostatic dressing that can be left in place during traumatic wound healing with future potential use in regenerative medicine applications.
Topics & Concepts
Degradation (telecommunications)HydrolysisHydrolytic degradationBattlefieldPolymerMaterials scienceShape-memory polymerEtherBiodegradationComposite materialChemical engineeringChemistryOrganic chemistryComputer scienceHistoryEngineeringAncient historyTelecommunicationsHemostasis and retained surgical itemsWound Healing and TreatmentsSurgical Sutures and Adhesives