Dapagliflozin dampens liver fibrosis induced by common bile duct ligation in rats associated with the augmentation of the hepatic Sirt1/AMPK/PGC1α/FoxO1 axis
Heba Hassan, Mahitab M. Nageeb, Heba Osama Mohammed, Walaa Samy, Amal Fawzy, Rofaida Afifi, Noha A.T. Abbas
Topics & Concepts
DapagliflozinAMPKFibrosisMedicineDiabetes mellitusType 2 Diabetes MellitusFOXO1Internal medicineEndocrinologyAntioxidantCanagliflozinPharmacologyChemistrySignal transductionBiochemistryEnzymeProtein kinase AProtein kinase BLiver Disease Diagnosis and TreatmentLiver physiology and pathologyPancreatic function and diabetes