Exploring the potential of iron-based metal–organic frameworks as peroxidase nanozymes for glucose detection with various secondary building units
Sivasankar Kulandaivel, Hsin‐Tsung Chen, Chia‐Her Lin, Yi-Chun Yeh
Abstract
colorimetric techniques. Using encapsulation, we incorporated glucose oxidase into the ZIF-90 PVP MOF and conducted a sequential reaction with the Fe-MOF to detect glucose. The results showed better peroxidase catalytic activity of the MIL-88B(Fe) (1,4-NDC) MOF and similar secondary building unit (SBU) Fe-MOFs were studied in other peroxidase nanozyme studies. When combined with an enzyme-encapsulating ZIF-90 PVP MOF, they could be sequentially employed for glucose detection purposes. This study highlights the potential of nanozymes as an alternative to natural enzymes, with promising applications in biosensing and beyond.
Topics & Concepts
Metal-organic frameworkPeroxidaseNanotechnologyMaterials scienceMetalEnvironmental chemistryChemistryMetallurgyOrganic chemistryEnzymeAdsorptionAdvanced Nanomaterials in CatalysisElectrochemical sensors and biosensorsAdvanced biosensing and bioanalysis techniques