A more sustainable and highly practicable synthesis of aliphatic isocyanides
Kevin A. Waibel, Roman Nickisch, N. Möhl, Rebecca Seim, Michaël A. R. Meier
Abstract
A more sustainable and easier applicable synthesis of aliphatic isocyanides in DMC is introduced using non-hazardous<italic>p</italic>-toluenesulfonyl chloride as dehydration reagent.
Topics & Concepts
ReagentDehydrationChemistrySustainable productionHazardous wasteOrganic chemistryChlorideCombinatorial chemistryWaste managementProduction (economics)EngineeringBiochemistryMacroeconomicsEconomicsMulticomponent Synthesis of HeterocyclesChemistry and Chemical EngineeringChemical Synthesis and Reactions