Development of an engineered thermostable amine dehydrogenase for the synthesis of structurally diverse chiral amines
Lei Liu, Donghao Wang, Fei‐Fei Chen, Zhi‐Jun Zhang, Qi Chen, Jian‐He Xu, Zhilong Wang, Gao‐Wei Zheng
Abstract
Structurally diverse chiral amines and amino alcohols were synthesized using an engineered thermostable amine dehydrogenase, demonstrating its extensive synthesis potential.
Topics & Concepts
Amine gas treatingChemistryCombinatorial chemistryCatalysisBiocatalysisOrganic chemistryReaction mechanismEnzyme Catalysis and ImmobilizationAmino Acid Enzymes and MetabolismPharmacogenetics and Drug Metabolism