Regioselective 1,2-carbosulfenylation of unactivated alkenes<i>via</i>directed nickel catalysis
Lin Zhu, Meng Xiao, Leipeng Xie, Qiuyang Shen, Wenyi Li, Lanlan Zhang, Chao Wang
Abstract
A removable bidentate picolinamide assisted regioselective 1,2-carbosulfenylation of unactivated alkenes with aryl/alkenylboronic acids and disulfide electrophiles has been developed with a cost-effective and air-stable Ni( ii ) precatalyst.
Topics & Concepts
RegioselectivityChemistryElectrophileCatalysisDenticityNickelArylDisulfide bondCombinatorial chemistryOrganic chemistryMedicinal chemistryAlkylBiochemistryMetalSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods