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Combined Catalpol and Tetramethylpyrazine Promote Axonal Plasticity in Alzheimer’s Disease by Inducing Astrocytes to Secrete Exosomes Carrying CDK5 mRNA and Regulating STAT3 Phosphorylation

Huize Chen, Chujun Deng, Zeyu Meng, Mengting Zhu, Ruoyu Yang, Jing Yuan, Shengxi Meng

2024Molecular Neurobiology20 citationsDOI

Topics & Concepts

TetramethylpyrazineCyclin-dependent kinase 5SecretionCell biologyMicrovesiclesPhosphorylationSynaptic plasticityNeuroscienceBiologyDiseasemicroRNAMedicineBiochemistryGenePathologyReceptorMitogen-activated protein kinase kinaseAlternative medicineProtein kinase ANeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanismsAlzheimer's disease research and treatments
Combined Catalpol and Tetramethylpyrazine Promote Axonal Plasticity in Alzheimer’s Disease by Inducing Astrocytes to Secrete Exosomes Carrying CDK5 mRNA and Regulating STAT3 Phosphorylation | Litcius